Inotersen

Inotersen is an antisense oligonucleotide that inhibits hepatic production of transthyretin (TTR) .

Product Specifications

CAS Number

[1492984-65-2]

Product Name Alternative

GSK-2998728; ISIS-420915

UNSPSC

12352208

Target

Transthyretin (TTR)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/inotersen.html

Purity

96.44

Solubility

10 mM in H2O

Smiles

[Inotersen]

Molecular Formula

C230H318N69O121P19S19

Molecular Weight

7183.08

References & Citations

[1]Benson MD, Waddington-Cruz M, Berk JL, et al. Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis. N Engl J Med. 2018;379 (1) :22-31.|[2]Mathew V, Wang AK. Inotersen: new promise for the treatment of hereditary transthyretin amyloidosis. Drug Des Devel Ther. 2019;13:1515-1525. Published 2019 May 6.