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ST8154AA1

ST8154AA1 is a part of antibody agent conjugates (ADCs) charged with HDAC inhibitor by a linker, shows antitumor activity[1].

Product Specifications

CAS Number

2247025-59-6

UNSPSC

12352203

Target

Drug-Linker Conjugates for ADC

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/st8154aa1.html

Solubility

10 mM in DMSO

Smiles

OC([C@H]1CC[C@H](CNC(CCCCCN2C(CC(SCCCCC[C@H](NC([C@H]3CCC(N3)=O)=O)C(NC4=CC=CC=C4)=O)C2=O)=O)=O)CC1)=O

Molecular Formula

C36H51N5O8S

Molecular Weight

713.88

References & Citations

[1]Cini E, et al. Antibody drug conjugates (ADCs) charged with HDAC inhibitor for targeted epigenetic modulation. Chem Sci. 2018 Jul 3;9 (31) :6490-6496.

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Traditional Cytotoxic Agents

Frequently Asked Questions

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