Thalidomide-O-amido-PEG2-C2-NH2
Thalidomide-O-amido-PEG2-C2-NH2 incorporates an E3 ligase ligand and a linker, can be an immunomodulater for the research of cancer.
Product Specifications
CAS Number
[1957235-74-3]
Product Name Alternative
Cereblon Ligand-Linker Conjugates 10; E3 Ligase Ligand-Linker Conjugates 24
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; PROTAC
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/thalidomide-o-amido-peg2-c2-nh2.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCOCCOCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
Molecular Formula
C21H26N4O8
Molecular Weight
462.45
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]ARYL SULFONOHYDRAZIDES. WO 2017/176958 A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
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