PDE7-IN-2
PDE7-IN-2 (compound 2) is a potent PDE7 (phosphodiesterase 7) inhibitor with IC50 value of 2.1 µM. PDE7-IN-2 has the potential for the research of parkinson’s disease[1].
Product Specifications
CAS Number
[107522-19-0]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pde7-in-2.html
Purity
99.0
Solubility
DMSO : 30 mg/mL (ultrasonic; warming)
Smiles
ClC1=CC(SC2=CC=CC=C2NC(C)=O)=C(C=C1)[N+]([O-])=O
Molecular Formula
C14H11ClN2O3S
Molecular Weight
322.77
References & Citations
[1]García AM, wt, al. Modulation of cAMP-specific PDE without emetogenic activity: new sulfide-like PDE7 inhibitors. J Med Chem. 2014 Oct 23;57 (20) :8590-607.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE7
Available Sizes
Curated Selection
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