2′,3′,5′-Triacetyl-5-azacytidine
2′,3′,5′-Triacetyl-5-azacytidine is an orally active proagent of 5-Azacytidine. 5-Azacytidine is an inhibitor of DNA methyltransferase[1].
Product Specifications
CAS Number
[10302-78-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-3-5-triacetyl-5-azacytidine.html
Purity
98.09
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(O[C@@H]1[C@H](OC(C)=O)[C@@H](COC(C)=O)O[C@H]1N2C(N=C(N)N=C2)=O)=O
Molecular Formula
C14H18N4O8
Molecular Weight
370.31
Precautions
H302, H315, H319, H335
References & Citations
[1]Ziemba A, et, al. Development of an oral form of azacytidine: 2'3'5'triacetyl-5-azacytidine. Chemother Res Pract. 2011;2011:965826.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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