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HS79

Product Specifications

UNSPSC Description

HS-79 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-79 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 1.57 μM.

Target Antigen

Fatty Acid Synthase (FASN)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/HS79.html

Solubility

10 mM in DMSO

Smiles

CC1=C(C)SC2=NC=NC(N[C@@H]3CCN(CC4=CC=CC=C4)C3)=C21

Molecular Weight

338.47

References & Citations

[1]Alwarawrah Y, et al. Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer. Cell Chem Biol. 2016 Jun 23;23(6):678-88.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-112522/HS79-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-112522/

Clinical Information

No Development Reported

CAS Number

2138838-56-7

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