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Sirt2-IN-2

Sirt2-IN-2 (Compound 10) is a selective Sirt2 inhibitor with an IC50 of 0.118 μM[1].

Product Specifications

CAS Number

[1862238-01-4]

UNSPSC

12352005

Target

Sirtuin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/sirt2-in-2.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=NC=C(CC2=CC=CC(OCC3=CN(CCOC)N=N3)=C2)S1)CSC4=NC(C)=CC(C)=N4

Molecular Formula

C24H27N7O3S2

Molecular Weight

525.65

References & Citations

[1]Schiedel M, et al. Structure-Based Development of an Affinity Probe for Sirtuin 2. Angew Chem Int Ed Engl. 2016 Feb 5;55 (6) :2252-6.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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