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Sirt2-IN-2

Product Specifications

UNSPSC Description

Sirt2-IN-2 (Compound 10) is a selective Sirt2 inhibitor with an IC50 of 0.118 μM[1].

Target Antigen

Sirtuin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage;Epigenetics

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/sirt2-in-2.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=NC=C(CC2=CC=CC(OCC3=CN(CCOC)N=N3)=C2)S1)CSC4=NC(C)=CC(C)=N4

Molecular Weight

525.65

References & Citations

[1]Schiedel M, et al. Structure-Based Development of an Affinity Probe for Sirtuin 2. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2252-6.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-112428/Sirt2-IN-2-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-112428/

Clinical Information

No Development Reported

CAS Number

1862238-01-4

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