BTO-1
Product Specifications
UNSPSC Description
BTO-1 is a Polo-like kinase (Plk) inhibitor. BTO-1 is primarily used for phosphorylation and dephosphorylation applications[1][2].
Target Antigen
Polo-like Kinase (PLK)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/bto-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=[N+]([O-])C2=CC(C#N)=CC([N+]([O-])=O)=C2S1)N
Molecular Weight
264.22
References & Citations
[1]Peters, U., et al. Probing cell-division phenotype space and Polo-like kinase function using small molecules. Nat Chem Biol 2, 618–626 (2006).|[2]Brennan IM, et al. Polo-like kinase controls vertebrate spindle elongation and cytokinesis. PLoS One. 2007;2(5):e409. Published 2007 May 2.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-112395/BTO-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-112395/
Clinical Information
No Development Reported
CAS Number
40647-02-7
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