Syk Inhibitor II (dihydrochloride dihydrate)
Selected Variant
HY-112390B
Size: 1 Each
Syk Inhibitor II dihydrochloride dihydrate is a potent, high selective and ATP-competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II dihydrochloride dihydrate inhibits 5-HT release from RBL-cells with an IC50 of 460 nM. Syk Inhibitor II dihydrochloride dihydrate shows less potent against other kinases and has anti-allergic effect[1].
Product Specifications
CAS Number
1965323-05-0
UNSPSC
12352005
Target
5-HT Receptor; Syk
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling; Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/syk-inhibitor-ii-dihydrochloride-dihydrate.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CN=C(NCCN)N=C1NC2=CC=CC(C(F)(F)F)=C2)N.[H]Cl.[H]Cl.O.O
Molecular Formula
C14H21Cl2F3N6O3
Molecular Weight
449.26
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MUC4
Price
Frequently Asked Questions
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