SB 202474
SB 202474, a negative analog of SB203580. SB 202474, which has no ability to inhibit p38 MAPK activity and is widely used as a negative control compound in p38 MAPK studies, also suppressed melanin synthesis induction[1].
Product Specifications
CAS Number
172747-50-1
UNSPSC
12352005
Target
P38 MAPK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sb-202474.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C2=NC(CC)=C(C3=CC=NC=C3)N2)C=C1
Molecular Formula
C17H17N3O
Molecular Weight
279.34
References & Citations
[1]Bellei B, et al. p38 regulates pigmentation via proteasomal degradation of tyrosinase. J Biol Chem. 2010;285 (10) :7288-7299.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
247071-Biotin 100 µL
HHEX (Hematopoietically Expressed Homeobox, HEX, HMPH, HOX11L-PEN, PRH, PRHX) (Biotin)
Sign In for Pricing
View Details AJB33933-01 25 mg
Ethyl 2- (4-bromophenyl) -1- (2,4-dichlorophenyl) -1H-4-imidazolecarboxylate
Sign In for Pricing
View Details AJB33933-02 50 mg
Ethyl 2- (4-bromophenyl) -1- (2,4-dichlorophenyl) -1H-4-imidazolecarboxylate
Sign In for Pricing
View Details