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CRTh2 antagonist 1

CRTh2 antagonist 1 is a CRTh2 antagonist with an IC50 of 89 nM.

Product Specifications

CAS Number

1379445-54-1

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Inflammation/Immunology; Endocrinology

Assay Protocol

https://www.medchemexpress.com/2-_5-Methyl-1-_2-_morpholinosulfonyl_benzyl_-3-phenyl-1H-pyrazol-4-yl_acetic_acid.html

Solubility

10 mM in DMSO

Smiles

O=C(O)CC1=C(C)N(CC2=CC=CC=C2S(=O)(N3CCOCC3)=O)N=C1C4=CC=CC=C4

Molecular Formula

C23H25N3O5S

Molecular Weight

455.53

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Andrés M, et al. 2- (1H-Pyrazol-4-yl) acetic acids as CRTh2 antagonists. Bioorg Med Chem Lett. 2013 Jun 1;23 (11) :3349-53.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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