ORL1 antagonist 1
ORL1 antagonist 1 is an opioid receptor-like 1 (ORL1) antagonist with an IC50 of 61 nM.
Product Specifications
CAS Number
1174985-59-1
UNSPSC
12352005
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ORL1_antagonist_1.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C2=CC=CN=C2)N(C3=NC=CC=C3Cl)N=C1CNC4CCCC4
Molecular Formula
C20H22ClN5
Molecular Weight
367.88
References & Citations
[1]Kobayashi K, et al. Discovery of novel arylpyrazole series as potent and selective opioid receptor-like 1 (ORL1) antagonists. Bioorg Med Chem Lett. 2009 Jul 1;19 (13) :3627-31.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NOP Receptor/ORL1
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