IDO1 and HDAC1 Inhibitor
Product Specifications
UNSPSC Description
IDO1 and HDAC1 Inhibitor (Compound 10) is a dual IDO1 and HDAC1 inhibitor with IC50s of 69.0 nM and 66.5 nM, respectively[1].
Target Antigen
HDAC; Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics;Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/IDO1_and_HDAC1_Inhibitor.html
Solubility
10 mM in DMSO
Smiles
BrC1=CC(N/C(C2=NON=C2NCCNC(C3=CC=C(C(NC4=C(N)C=CC=C4)=O)C=C3)=O)=N/O)=CC=C1F
Molecular Weight
597.40
References & Citations
[1]Fang K, et al. Discovery of Novel Indoleamine 2,3-Dioxygenase 1 (IDO1) and Histone Deacetylase (HDAC) Dual Inhibitors. ACS Med Chem Lett. 2018 Mar 26;9(4):312-317.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-112147/IDO1-and-HDAC1-Inhibitor-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-112147/
Clinical Information
No Development Reported
CAS Number
2227044-16-6
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