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AGI-25696

AGI-25696 is a methionine adenosyltransferase 2A (MATA2) inhibitors useful for treatment of cancer. AGI-25696 blocks growth of MTAP-deleted tumors in vivo.

Product Specifications

CAS Number

[2201066-35-3]

UNSPSC

12352005

Target

Methionine Adenosyltransferase (MAT)

Type

Reference compound

Related Pathways

Epigenetics; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/AGI-25696.html

Solubility

10 mM in DMSO

Smiles

O=C1C(C2=CC=C3N=CC=CC3=C2)=CNC4=C(C5=CC=CC=C5)C(C6=CC=CC=C6)=NN14

Molecular Formula

C27H18N4O

Molecular Weight

414.46

References & Citations

[1]Agios. Targeting MAT2A in MTAP-deleted Cancers. Presented at the American Association for Cancer Research (AACR) Annual Meeting, April 14-18, 2018, Chicago, IL, USA

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-112129/AGI-25696-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-112129/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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