AGI-25696
AGI-25696 is a methionine adenosyltransferase 2A (MATA2) inhibitors useful for treatment of cancer. AGI-25696 blocks growth of MTAP-deleted tumors in vivo.
Product Specifications
CAS Number
[2201066-35-3]
UNSPSC
12352005
Target
Methionine Adenosyltransferase (MAT)
Type
Reference compound
Related Pathways
Epigenetics; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/AGI-25696.html
Solubility
10 mM in DMSO
Smiles
O=C1C(C2=CC=C3N=CC=CC3=C2)=CNC4=C(C5=CC=CC=C5)C(C6=CC=CC=C6)=NN14
Molecular Formula
C27H18N4O
Molecular Weight
414.46
References & Citations
[1]Agios. Targeting MAT2A in MTAP-deleted Cancers. Presented at the American Association for Cancer Research (AACR) Annual Meeting, April 14-18, 2018, Chicago, IL, USA
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-112129/AGI-25696-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-112129/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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