Revospirone

Revospirone (BAY Vq 7813) is a partial agonist of the 5-HT1A receptor with a Ki of 2 nmol/L. Revospirone inhibits adenylate cyclase activity with an IC50 of 124 nmol/L[1].

Product Specifications

CAS Number

[95847-87-3]

Product Name Alternative

BAY Vq 7813

UNSPSC

12352005

Target

5-HT Receptor; Adenylate Cyclase

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/revospirone.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(S(=O)(N1CCCN3CCN(CC3)C4=NC=CC=N4)=O)C=CC=C2

Molecular Formula

C18H21N5O3S

Molecular Weight

387.46

References & Citations

[1]Löscher, W et al. The behavioural responses to 8-OH-DPAT, ipsapirone and the novel 5-HT1A receptor agonist Bay Vq 7813 in the pig. Naunyn-Schmiedeberg's archives of pharmacology vol. 342,3 (1990) : 271-7.