(+) -Erinacin A
(+) -Erinacin A (Erinacine A) is a cyanoditerpenoid isolated from Hericium erinaceus with anticancer, anti-inflammatory and neuroprotective activities. (+) -Erinacin A can induce cancer cell death by activating extrinsic and intrinsic apoptosis pathways. (+) -Erinacin A can also inhibit the expression of NO synthase (iNOS) and the production of nitrotyrosine to exert inflammatory and neuroprotective effects, thereby reducing ischemic brain damage[1][2][3][4][5].
Product Specifications
CAS Number
156101-08-5
Product Name Alternative
Erinacine A
UNSPSC
12352005
Target
Apoptosis; Bcl-2 Family; Caspase; Histone Acetyltransferase; JNK; NF-κB; NO Synthase; p38 MAPK
Type
Reference compound
Related Pathways
Apoptosis; Epigenetics; Immunology/Inflammation; MAPK/ERK Pathway; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/plus-erinacin-a.html
Purity
99.97
Solubility
Ethanol : 10 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@@H]2[C@@](CC[C@]3(C)C4=C(C(C)C)CC3)(C)C4=CC=C(C=O)C2)OC1
Molecular Formula
C25H36O6
Molecular Weight
432.55
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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