(-) -Ibuprofenamide
(-) -Ibuprofenamide is an amide proagent of Ibuprofen with anti-inflammatory activity[1]. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[2].
Product Specifications
CAS Number
121839-78-9
Product Name Alternative
(R) -Ibuprofenamide
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ibuprofenamide.html
Solubility
10 mM in DMSO
Smiles
CC(C)CC1=CC=C([C@@H](C)C(N)=O)C=C1
Molecular Formula
C13H19NO
Molecular Weight
205.30
References & Citations
[1]Shanbhag VR, et al. Ester and amide prodrugs of ibuprofen and naproxen: synthesis, anti-inflammatory activity, and gastrointestinal toxicity. J Pharm Sci. 1992 Feb;81 (2) :149-54.|[2]Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61 (1) :2-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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