MI-1
MI-1 inhibits Menin-MLL interaction with an IC50 of 1.9 μM[1].
Product Specifications
CAS Number
433311-07-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mi-1.html
Solubility
10 mM in DMSO
Smiles
CC1(C)CN=C(N2CCN(C3=C(C4=C(CCCC4)S5)C5=NC=N3)CC2)S1
Molecular Formula
C19H25N5S2
Molecular Weight
387.57
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Vedadi M, et al. Targeting human SET1/MLL family of proteins. Protein Sci. 2017 Apr;26 (4) :662-676. doi: 10.1002/pro.3129. Epub 2017 Mar 6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6493835-01 0.1 mL
Platelet Derived Growth Factor Receptor Type B (PDGFRb) (Biotin)
Sign In for Pricing
View Details MBS6493835-02 5x 0.1 mL
Platelet Derived Growth Factor Receptor Type B (PDGFRb) (Biotin)
Sign In for Pricing
View Details 
F54918-0.08ML 0.08 mL
Pigment epithelium-derived factor Antibody / PEDF / SERPINF1
Sign In for Pricing
View Details 128853-ML750 100 µL
KLF16 (Kruppel-like Factor 16, Basic Transcription Element Binding Protein 4, BTE-binding Protein 4, BTEB4, DRRF, Novel Sp1-like Zinc Finger Transcription Factor 2, NSLP2, Transcription Factor BTEB4, Transcription Factor NSLP2) (MaxLight 750) discontinued
Sign In for Pricing
View Details 
129392-PE 100 µL
MAPK1 (Mitogen-activated Protein Kinase 1, MAPK 1, MAP Kinase 1, ERT1, Extracellular Signal-regulated Kinase 2, ERK2, ERK-2, ERK, MAP Kinase Isoform p42, Mitogen-activated Protein Kinase 2, MAP Kinase 2, MAPK 2, MAPK2, p41mapk, p42-MAPK, P42MAPK, PRKM1, PRKM2) (PE) discontinued
Sign In for Pricing
View Details 2064405/7 1 Each
FLASK, VOLUMETRIC, WITHOUT POUROUT CLASS 'A’, AMBER
Sign In for Pricing
View Details