MI-1
MI-1 inhibits Menin-MLL interaction with an IC50 of 1.9 μM[1].
Product Specifications
CAS Number
433311-07-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mi-1.html
Solubility
10 mM in DMSO
Smiles
CC1(C)CN=C(N2CCN(C3=C(C4=C(CCCC4)S5)C5=NC=N3)CC2)S1
Molecular Formula
C19H25N5S2
Molecular Weight
387.57
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Vedadi M, et al. Targeting human SET1/MLL family of proteins. Protein Sci. 2017 Apr;26 (4) :662-676. doi: 10.1002/pro.3129. Epub 2017 Mar 6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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