MI-1

MI-1 inhibits Menin-MLL interaction with an IC50 of 1.9 μM[1].

Product Specifications

CAS Number

[433311-07-0]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mi-1.html

Solubility

10 mM in DMSO

Smiles

CC1(C)CN=C(N2CCN(C3=C(C4=C(CCCC4)S5)C5=NC=N3)CC2)S1

Molecular Formula

C19H25N5S2

Molecular Weight

387.57

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Vedadi M, et al. Targeting human SET1/MLL family of proteins. Protein Sci. 2017 Apr;26 (4) :662-676. doi: 10.1002/pro.3129. Epub 2017 Mar 6.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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