3,3'-Diethyl-9-methylthiacarbocyanine (iodide)
3,3'-Diethyl-9-methylthiacarbocyanine iodide is a cyanine dye, also a tau aggregation inhibitor, with an IC50 value of 0.28 μM for tau. 3,3'-Diethyl-9-methylthiacarbocyanine iodide can cause misfunction of the microtubule cytoskeleton. 3,3'-Diethyl-9-methylthiacarbocyanine iodide can be used for researching Alzheimer’s disease[1].
Product Specifications
CAS Number
[3065-79-0]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/3-3-diethyl-9-methylthiacarbocyanine-iodide.html
Purity
98.93
Solubility
DMSO : 4.17 mg/mL (ultrasonic)
Smiles
CC(/C=C1SC2=CC=CC=C2N/1CC)=C\C3=[N+](CC)C4=CC=CC=C4S3.[I-]
Molecular Formula
C22H23IN2S2
Molecular Weight
506.47
Precautions
H315, H319, H335
References & Citations
[1]Chang E, et al. Structure-activity relationship of cyanine tau aggregation inhibitors. J Med Chem. 2009 Jun 11;52 (11) :3539-47.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Recombinant Acinetobacter baumannii UPF0060 membrane protein A1S_1909 (A1S_1909)
Recombinant Acinetobacter baumannii UPF0060 membrane protein A1S_1909 (A1S_1909)
Recombinant Acinetobacter baumannii UPF0060 membrane protein A1S_1909 (A1S_1909)