SNIPER(TACC3)-1 (hydrochloride)
Product Specifications
UNSPSC Description
SNIPERTACC3-1 hydrochloride targets the TACC3 protein for degradation via the ubiquitin-proteasome pathway based on IAP ligand. SNIPERTACC3-1 hydrochloride induces cancer cell death[1].
Target Antigen
SNIPERs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sniper-tacc3-1-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCOCCOCCNC([C@H](CC(C)C)NC([C@H]([C@@H](CC1=CC=CC=C1)N)O)=O)=O)C2=CC=C(C3=NC(CNC4=NC=CC(NCC(C)C)=N4)=CS3)C=C2.[H]Cl
Molecular Weight
840.47
References & Citations
[1]Ohoka N, et al. Cancer cell death induced by novel small molecules degrading the TACC3 protein via the ubiquitin-proteasome pathway. Cell Death Dis. 2014 Nov 6;5:e1513.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-111876A/SNIPER-TACC3-1-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-111876A/
Clinical Information
No Development Reported
Curated Selection
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