PROTAC CRABP-II Degrader-3
PROTAC CRABP-II Degrader-3 is a potent cellular retinoic acid binding protein (CRABP-II) degrader based on IAP ligand[1].
Product Specifications
CAS Number
[1225383-41-4]
UNSPSC
12352005
Target
PROTACs; SNIPERs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-crabp-ii-degrader-3.html
Solubility
10 mM in DMSO
Smiles
CC(/C=C/C=C(/C=C/C1=C(/C(CCC(C)1C)=N/OCC(NCCOCCOCCOCCOC([C@H](CC(C)C)NC([C@@H](O)[C@H](N)CC2=CC=CC=C2)=O)=O)=O)C)C)=C\C(O)=O
Molecular Formula
C46H68N4O11
Molecular Weight
853.05
References & Citations
[1]Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019 Jan 25;17:160-176.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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