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PROTAC CRABP-II Degrader-2

PROTAC CRABP-II Degrader-2 is a potent cellular retinoic acid binding protein (CRABP-II) degrader based on IAP ligand[1].

Product Specifications

CAS Number

[1225383-38-9]

UNSPSC

12352005

Target

PROTACs; SNIPERs

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/protac-crabp-ii-degrader-2.html

Solubility

10 mM in DMSO

Smiles

CC(/C=C/C=C(/C=C/C1=C(/C(CCC(C)1C)=N/OCC(NCCOCCOCCOC([C@H](CC(C)C)NC([C@@H](O)[C@H](N)CC2=CC=CC=C2)=O)=O)=O)C)C)=C\C(O)=O

Molecular Formula

C44H64N4O10

Molecular Weight

809.00

References & Citations

[1]Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019 Jan 25;17:160-176.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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