LJ570
LJ570 is a PPARα/PPARγ dual agonist with EC50s of 1.05 and 0.12 μM, respectively[1].
Product Specifications
CAS Number
2252488-69-8
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/LJ570.html
Solubility
10 mM in DMSO
Smiles
OC([C@@H](OC1=CC=C(C2=CC=CC=C2)C=C1)CC3=CC=C(C4=CC=CC=C4)C=C3)=O
Molecular Formula
C27H22O3
Molecular Weight
394.46
References & Citations
[1]Laghezza A, et al. Identification of the First PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation. J Med Chem. 2018 Sep 27;61 (18) :8282-8298.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARα; PPARγ
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC-4585.2 100 g
L-Ornithine monohydrochloride pure DAB (pharma grade)
Sign In for Pricing
View Details 
MBS2577996-01 24 Tests (Limit 1)
Human SOD2 (Superoxide Dismutase 2, Mitochondrial) ELISA Kit
Sign In for Pricing
View Details MBS2577996-02 48 Tests
Human SOD2 (Superoxide Dismutase 2, Mitochondrial) ELISA Kit
Sign In for Pricing
View Details