JAK-IN-4
Product Specifications
UNSPSC Description
JAK-IN-4 is a proagent of a JAK inhibitor, effective in murine collagen induced arthritis model[1].
Target Antigen
JAK
Type
Reference compound
Related Pathways
Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/JAK-IN-4.html
Solubility
10 mM in DMSO
Smiles
O=P(OC[C@@H](NC1=C(C(N)=O)C=NN2C1=CC(C3=CC=CC=C3)=C2)[C@H](O)C)(O[Na])O[Na]
Molecular Weight
464.32
References & Citations
[1]Spergel SH, et al. Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis. ACS Med Chem Lett. 2019 Feb 13;10(3):306-311.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-111749/JAK-IN-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-111749/
Clinical Information
No Development Reported
CAS Number
1400877-37-3
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