RXFP3/4 agonist 1

RXFP3/4 agonist 1 is an agonist of relaxin family peptide 3/4 receptor (RXFP3/4), with EC50s of 82/2 nM, respectivley. RXFP3/4 agonist 1 increases food intake in rats[1].

Product Specifications

CAS Number

[2351104-40-8]

UNSPSC

12352005

Target

RXFP Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/RXFP3-4_agonist_1.html

Solubility

10 mM in DMSO

Smiles

CCC1=C(NC=C2/C=N/NC(NCCC3=CC=C(Cl)C=C3)=N)C2=CC(O)=C1

Molecular Formula

C20H22ClN5O

Molecular Weight

383.87

References & Citations

[1]DeChristopher B, et al. Discovery of a small molecule RXFP3/4 agonist that increases food intake in rats upon acute central administration. Bioorg Med Chem Lett. 2019 Apr 15;29 (8) :991-994.