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JAK-IN-5

JAK-IN-5 is an inhibitor of JAK extracted from patent US20170121327A1, compound example 283.

Product Specifications

CAS Number

2096999-92-5

UNSPSC

12352005

Target

JAK

Type

Reference compound

Related Pathways

Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/JAK_inhibitor_1.html

Solubility

10 mM in DMSO

Smiles

CN1CCC(N2CC(N=C(C3=NNC4=C3C=CC(C5=C(CC)C=C(O)C(F)=C5)=C4)N6)=C6CC2)CC1

Molecular Formula

C27H31FN6O

Molecular Weight

474.57

References & Citations

[1]Paul R. Fatheree, et al. JAK Kinase Inhibitor Compounds for Treatment of Respiratory Disease. US20170121327A1|[2]Venkat R, et al. Methods of treatment using a jak inhibitor compound. US20180311226.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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