Mcl1-IN-3
Mcl1-IN-3 is an inhibitor of Mcl1 extracted from patent WO2015153959A2, compound example 57; has an IC50 and Ki of 0.67 and 0.13 μM, respectively.
Product Specifications
CAS Number
[1814891-79-6]
UNSPSC
12352005
Hazard Statement
H302
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Mcl1-IN-3.html
Solubility
10 mM in DMSO
Smiles
CC1=NN(CC2=CC=C(OC3=CC(C)=C(Cl)C(C)=C3)C=C2)C4=C1C(C(O)=O)=CC(C5=CC=CO5)=N4
Molecular Formula
C27H22ClN3O4
Molecular Weight
487.93
Precautions
P264-P270-P330-P501
References & Citations
[1]Nikolovska-Coleska Z, et al. Pyrazolopyridines as inhibitors of Mcl-1 and and their preparation. WO2015153959A2
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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