Mcl1-IN-3

Mcl1-IN-3 is an inhibitor of Mcl1 extracted from patent WO2015153959A2, compound example 57; has an IC50 and Ki of 0.67 and 0.13 μM, respectively.

Product Specifications

CAS Number

[1814891-79-6]

UNSPSC

12352005

Hazard Statement

H302

Target

Bcl-2 Family

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Mcl1-IN-3.html

Solubility

10 mM in DMSO

Smiles

CC1=NN(CC2=CC=C(OC3=CC(C)=C(Cl)C(C)=C3)C=C2)C4=C1C(C(O)=O)=CC(C5=CC=CO5)=N4

Molecular Formula

C27H22ClN3O4

Molecular Weight

487.93

Precautions

P264-P270-P330-P501

References & Citations

[1]Nikolovska-Coleska Z, et al. Pyrazolopyridines as inhibitors of Mcl-1 and and their preparation. WO2015153959A2

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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