IKK2-IN-3
IKK2-IN-3 (Compound 8) is a potent IKK2 inhibitor with an IC50 of 0.075 μM[1].
Product Specifications
CAS Number
916985-21-2
UNSPSC
12352005
Target
IKK
Type
Reference compound
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ikk2-in-3.html
Purity
98.0
Solubility
DMSO : 10 mg/mL (ultrasonic; warming)
Smiles
O=C(C1=C(OCC2=CC=C(S(=O)(C)=O)C=C2)C=C(N3C4=CC(OC)=C(OC)C=C4N=C3)S1)N
Molecular Formula
C22H21N3O6S2
Molecular Weight
487.55
References & Citations
[1]Xie HZ, et al. Pharmacophore modeling and hybrid virtual screening for the discovery of novel IκB kinase 2 (IKK2) inhibitors. J Biomol Struct Dyn. 2011 Aug;29 (1) :165-79.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IKK-β
Available Sizes
Frequently Asked Questions
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