LY3104607

LY3104607 is a potent and selective G protein-coupled receptor 40 (GPR40) agonist. LY3104607 can be used in research of diabetes[1].

Product Specifications

CAS Number

[1795232-22-2]

UNSPSC

12352005

Target

Free Fatty Acid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ly3104607.html

Solubility

10 mM in DMSO

Smiles

CC(C=CC=C1C)=C1C2=NN3C(C=CC(COC4=CC=C([C@@H](C#CC)CC(O)=O)C=C4)=C3)=N2

Molecular Formula

C27H25N3O3

Molecular Weight

439.51

References & Citations

[1]Hamdouchi C, et, al. Discovery of LY3104607: A Potent and Selective G Protein-Coupled Receptor 40 (GPR40) Agonist with Optimized Pharmacokinetic Properties to Support Once Daily Oral Treatment in Patients with Type 2 Diabetes Mellitus. J Med Chem. 2018 Feb 8;61 (3) :934-945.