AZD-7295
AZD-7295 is a HCV NS5A protein inhibitor, with an EC50 of 7 nM for GT-1b replicon[1][2].
Product Specifications
CAS Number
[929890-64-2]
UNSPSC
12352005
Target
HCV Protease
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/azd-7295.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(C2=CC(NC(C3CC3)=O)=CC=C2OC(F)(F)F)C=C1)NC4=CC=C(CN5CCN(S(=O)(CCC)=O)CC5)C=C4
Molecular Formula
C32H35F3N4O5S
Molecular Weight
644.70
References & Citations
[1]Erik De Clercq, et al. Current race in the development of DAAs (direct-acting antivirals) against HCV. Biochem Pharmacol. 2014 Jun 15;89 (4) :441-52.|[2]Min Gao, et al. Antiviral activity and resistance of HCV NS5A replication complex inhibitors. Curr Opin Virol. 2013 Oct;3 (5) :514-20.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-111087/AZD-7295-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-111087/
Scientific Category
Reference compound1
Clinical Information
Phase 1
Curated Selection
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