CPI-905
CPI-905 is a potent, selective, and cell-active EZH2 inhibitor[1].
Product Specifications
CAS Number
[931078-17-0]
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cpi-905.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(OC)=C(OCCO2)C2=C1)NCC3=C(C)C=C(C)NC3=O
Molecular Formula
C18H20N2O5
Molecular Weight
344.36
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]William D Bradley, et al. EZH2 inhibitor efficacy in non-Hodgkin's lymphoma does not require suppression of H3K27 monomethylation. Chem Biol. 2014 Nov 20;21 (11) :1463-75.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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