Capsiconiate
Capsiconiate (Coniferyl (E) -8-methyl-6-nonenoate) is a TRPV1 agonist (EC50= 3.2 μM) . Capsiconiate can be used to study TRPV1-mediated diseases such as pain, inflammation, and epilepsy (EC50= 3.2 μM) [1].
Product Specifications
CAS Number
946572-73-2
Product Name Alternative
Coniferyl (E) -8-methyl-6-nonenoate
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
TRP Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/capsiconiate.html
Solubility
10 mM in DMSO
Smiles
CC(C)/C=C/CCCCC(OC/C=C/C1=CC=C(O)C(OC)=C1)=O
Molecular Formula
C20H28O4
Molecular Weight
332.43
Precautions
H302, H315, H319, H335
References & Citations
[1]Kobata K, et al. Isolation of coniferyl esters from Capsicum baccatum L., and their enzymatic preparation and agonist activity for TRPV1. Phytochemistry. 2008 Mar;69 (5) :1179-84.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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