Capsiconiate

Capsiconiate (Coniferyl (E) -8-methyl-6-nonenoate) is a TRPV1 agonist (EC50= 3.2 μM) . Capsiconiate can be used to study TRPV1-mediated diseases such as pain, inflammation, and epilepsy (EC50= 3.2 μM) [1].

Product Specifications

CAS Number

[946572-73-2]

Product Name Alternative

Coniferyl (E) -8-methyl-6-nonenoate

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

TRP Channel

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/capsiconiate.html

Solubility

10 mM in DMSO

Smiles

CC(C)/C=C/CCCCC(OC/C=C/C1=CC=C(O)C(OC)=C1)=O

Molecular Formula

C20H28O4

Molecular Weight

332.43

Precautions

H302, H315, H319, H335

References & Citations

[1]Kobata K, et al. Isolation of coniferyl esters from Capsicum baccatum L., and their enzymatic preparation and agonist activity for TRPV1. Phytochemistry. 2008 Mar;69 (5) :1179-84.