LJP 1586
LJP 1586 is an amine-based inhibitor of semicarbazide-sensitive amine oxidase (SSAO) activity. LJP 1586 is an orally active, potent and selective inhibitor of rodent and human SSAO activity, with IC50 values between 4 and 43 nM[1].
Product Specifications
CAS Number
955037-42-0
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ljp-1586.html
Solubility
10 mM in DMSO
Smiles
[H]Cl.NC/C(CC1=CC=C(OC)C=C1)=C\F
Molecular Formula
C11H15ClFNO
Molecular Weight
231.69
References & Citations
[1]O'Rourke AM, et al. Anti-inflammatory effects of LJP 1586 [Z-3-fluoro-2- (4-methoxybenzyl) allylamine hydrochloride], an amine-based inhibitor of semicarbazide-sensitive amine oxidase activity. J Pharmacol Exp Ther. 2008 Feb;324 (2) :867-75.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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