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Displurigen

Displurigen (NSC375009) disrupts human embryonic stem cell pluripotency by targeting HSPA8. Displurigen inhibits ATPase activity of HSP70 (IC50 = 225 μM) [1].

Product Specifications

CAS Number

[96156-26-2]

Product Name Alternative

NSC375009

UNSPSC

12352005

Hazard Statement

H315, H319

Target

HSP

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/displurigen.html

Purity

98.48

Solubility

DMSO : 7 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=CC=CC(O)=C12)C=C(C3=CC=CC=C3)S2(=O)=O

Molecular Formula

C15H10O4S

Molecular Weight

286.30

Precautions

H315, H319

References & Citations

[1]Yijie Geng, et al. A Chemical Biology Study of Human Pluripotent Stem Cells Unveils HSPA8 as a Key Regulator of Pluripotency. Stem Cell Reports. 2015 Dec 8;5 (6) :1143-1154.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-111002/Displurigen-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-111002/Displurigen-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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