Displurigen
Displurigen (NSC375009) disrupts human embryonic stem cell pluripotency by targeting HSPA8. Displurigen inhibits ATPase activity of HSP70 (IC50 = 225 μM) [1].
Product Specifications
CAS Number
[96156-26-2]
Product Name Alternative
NSC375009
UNSPSC
12352005
Hazard Statement
H315, H319
Target
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/displurigen.html
Purity
98.48
Solubility
DMSO : 7 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC=CC(O)=C12)C=C(C3=CC=CC=C3)S2(=O)=O
Molecular Formula
C15H10O4S
Molecular Weight
286.30
Precautions
H315, H319
References & Citations
[1]Yijie Geng, et al. A Chemical Biology Study of Human Pluripotent Stem Cells Unveils HSPA8 as a Key Regulator of Pluripotency. Stem Cell Reports. 2015 Dec 8;5 (6) :1143-1154.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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