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JNJ-20788560

JNJ-20788560 is a selective and orally active delta opioid receptor agonist with an affinity of 2.0 nM for DOR (rat brain cortex binding assay) . JNJ-20788560 also is a potent and efficacious antihyperalgesic agent that does not produce respiratory depression, pharmacologic tolerance, or physical dependence. JNJ-20788560 can be used for the research of the relief of inflammatory hyperalgesia[1].

Product Specifications

CAS Number

825649-28-3

UNSPSC

12352005

Target

Opioid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/jnj-20788560.html

Purity

98.05

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C2/C(C3=CC=CC=C3OC2=C1)=C4CC(CC5)NC5C/4)N(CC)CC

Molecular Formula

C25H28N2O2

Molecular Weight

388.50

References & Citations

[1]Codd EE, et al. JNJ-20788560 [9- (8-azabicyclo[3.2.1]oct-3-ylidene) -9H-xanthene-3-carboxylic acid diethylamide], a selective delta opioid receptor agonist, is a potent and efficacious antihyperalgesic agent that does not produce respiratory depression, pharmacologic tolerance, or physical dependence. J Pharmacol Exp Ther. 2009 Apr;329 (1) :241-51.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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