CMP8
CMP8, a selective ligand for estrogen receptor, binds to the mutant estrogen receptor ligand binding domain (ERLBD) . CMP8 exhibits IC50 values of 29 nM , 41 nM, 1100 nM and 2200 nM for MGERα, MGRERα, hERα and hERβ, respectively[1][2].
Product Specifications
CAS Number
[851107-28-3]
UNSPSC
12352005
Target
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cmp8.html
Solubility
10 mM in DMSO
Smiles
O=C1CCC2(CC3=CC=C(Cl)C=C3)CC4=C(C=CC(O)=C4)C2=C1C5=CC=C(OCCN6CCCCC6)C=C5
Molecular Formula
C33H34ClNO3
Molecular Weight
528.08
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-110392/CMP8-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-110392/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERα; ERβ
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