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Xanthine amine congener (dihydrochloride)

Xanthine amine congener dihydrochloride (XAC dihydrochloride) is a potent Adenosine A1 receptor and A2 receptor antagonist with IC50 values of 1.8 and 114 nM, respectively. Xanthine amine congener acts as a convulsant agent in mice model[1].

Product Specifications

CAS Number

[1962928-23-9]

Product Name Alternative

XAC (dihydrochloride)

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Adenosine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/xanthine-amine-congener-dihydrochloride.html

Solubility

10 mM in DMSO

Smiles

O=C1N(C(C2=C(N1CCC)N=C(C3=CC=C(C=C3)OCC(NCCN)=O)N2)=O)CCC.Cl.Cl

Molecular Formula

C21H30Cl2N6O4

Molecular Weight

501.41

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]P F Morgan, et al.Potent Convulsant Actions of the Adenosine Receptor Antagonist, Xanthine Amine Congener (XAC) . Life Sci. 1989;45 (8) :719-28

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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