ONO-8130
ONO-8130 is an orally active and selective prostanoid EP1 receptor antagonist. ONO-8130 blocks phosphorylation of ERK in the L6 spinal cord. ONO-8130 relieves bladder pain in mice with cyclophosphamide-induced cystitis. ONO-8130 can be used for interstitial cystitis research[1].
Product Specifications
CAS Number
[459841-96-4]
UNSPSC
12352005
Target
PERK; Prostaglandin Receptor
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; GPCR/G Protein
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ono-8130.html
Solubility
10 mM in DMSO
Smiles
O=[S](N(C(C=C(CCC1)C1=C2)=C2OCC(C=C3)=CC=C3C(O)=O)CC(C)C)(C4=NC(C)=CS4)=O
Molecular Formula
C25H28N2O5S2
Molecular Weight
500.63
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-110198/ONO-8130-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-110198/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EP
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Thioredoxin domain containing 9 (TXNDC9) Human siRNA Oligo Duplex (Locus ID 10190)
PIC 401-N-A5-B7541 Fire & Disaster Signs & Labels (Adhesive)
