PDI-IN-1
PDI-IN-1 (Compound P1) is a cell-permeable human protein disulfide isomerase (PDI) inhibitor with an IC50 of 1.7 μM. PDI-IN-1 has anti-cancer activity.
Product Specifications
CAS Number
[1461648-55-4]
UNSPSC
12352005
Target
PDI
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pdi-in-1.html
Solubility
10 mM in DMSO
Smiles
C=CS(OC(C=C1)=CC=C1C[C@@H](C(NCCCC#C)=O)NC([C@@H](NC(OC(C)(C)C)=O)CC2=CC=CC=C2)=O)(=O)=O
Molecular Formula
C30H37N3O7S
Molecular Weight
583.70
References & Citations
[1]Ge J, Zhang C J, et al. Small molecule probe suitable for in situ profiling and inhibition of protein disulfide isomerase[J]. ACS chemical biology, 2013, 8 (11) : 2577-2585.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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