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UNC2327

UNC2327 is an allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) .

Product Specifications

CAS Number

[1426152-53-5]

UNSPSC

12352005

Target

Histone Methyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/unc2327.html

Purity

99.70

Solubility

DMF : 10 mg/mL (ultrasonic; warming)

Smiles

O=C(NCC(N1CCCCC1)=O)NC2=CC3=C(N=NS3)C=C2

Molecular Formula

C14H17N5O2S

Molecular Weight

319.38

References & Citations

[1]Liu F, et al. Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors. J Med Chem. 2013 Mar 14;56 (5) :2110-24.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PRMT3

Curated Selection

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