Procaspase-IN-5
Procaspase-IN-5 is a human DNA polymerase λ inhibitor. Procaspase-IN-5 has DNA polymerization function and TdT function with an IC50 value of 5.9 μM and 4.5 μM, respectively. Procaspase-IN-5 can be used for the research of cancer[1].
Product Specifications
CAS Number
[1489285-17-7]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/procaspase-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C1/C(SC(N1)=S)=C/C(C=C2)=CC([N+]([O-])=O)=C2SC3=C(C=CC=C3)C
Molecular Formula
C17H12N2O3S3
Molecular Weight
388.48
References & Citations
[1]Strittmatter T, et al. Expanding the scope of human DNA polymerase λ and β inhibitors. ACS Chem Biol. 2014 Jan 17;9 (1) :282-90.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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