CTA056
CTA056 is an ITK (IL-2-inducible T-cell kinase) inhibitor with an IC50 of 0.1 μM. CTA056 selectively targets malignant T cells and modulates oncomirs. CTA056 induces apoptosis and is a potential therapeutic agent for the research of T-cell leukemia and lymphoma[1].
Product Specifications
CAS Number
1265822-30-7
UNSPSC
12352005
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cta056.html
Solubility
10 mM in DMSO
Smiles
O=C1C(CC2=CC=CC=C2)=NC3=C(N1)C=C(N=C4C5=CC=C(C6=CC=NC=C6)C=C5)C(N4CCCN7CCCCC7)=C3
Molecular Formula
C35H34N6O
Molecular Weight
554.68
References & Citations
[1]Guo W, et al. Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs. Mol Pharmacol. 2012 Nov;82 (5) :938-47.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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