PK44 (phosphate)

PK44 phosphate is a potent dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 value of 15.8 nM[1].

Product Specifications

CAS Number

[1017682-66-4]

UNSPSC

12352005

Target

Dipeptidyl Peptidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/pk44-phosphate.html

Solubility

10 mM in DMSO

Smiles

O=P(O)(O)O.FC(F)(C1=NN=C2N1CCN(C(C[C@H](N)CC(C3=CC=C4F)=NNC3=C4F)=O)C2)F

Molecular Formula

C17H19F5N7O5P

Molecular Weight

527.34

References & Citations

[1]Adrian Maddaford, et al. Indazoles for use as dpp-iv inhibitors. WO2008040995A1 (compound 67)

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

DPP-4

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