Dexrazoxane (monohydrochloride)

Dexrazoxane monohydrochloride is the hydrochloride of Dexrazoxane (HY-B0581) . Dexrazoxane can prevent or reduce cardiac damage and is an iron chelator and apoptosis inducer. Dexrazoxane has cardioprotective, anti-inflammatory, antioxidant, anti-tumor and neuroprotective activities and inhibits ferroptosis[1].

Product Specifications

CAS Number

[1263283-43-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/dexrazoxane-monohydrochloride.html

Solubility

10 mM in DMSO

Smiles

C[C@H](N(C1)CC(NC1=O)=O)CN(C2)CC(NC2=O)=O.[H]Cl

Molecular Formula

C11H17ClN4O4

Molecular Weight

304.73

Precautions

H302, H315, H319, H335

References & Citations

[1]Lipshultz SE, et al. The effect of dexrazoxane on myocardial injury in doxorubicin-treated children with acute lymphoblastic leukemia. N Engl J Med. 2004 Jul 8;351 (2) :145-53.