CL-82198 (hydrochloride)

CL-82198 hydrochloride is a selective inhibitor of MMP-13. CL-82198 hydrochloride binds to the entire S1’ pocket of MMP-13, which is the basis of its selectivity against MMP-1, MMP-9, and TACE[1].

Product Specifications

CAS Number

[1188890-36-9]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

MMP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/cl-82198-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC2=C(C=CC=C2)O1)NCCCCN3CCOCC3.Cl

Molecular Formula

C17H23ClN2O3

Molecular Weight

338.83

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]James M. Chen, Frances C. Nelson, Jeremy I. Levin, Dominick Mobilio, Franklin J. Moy, Ramaswamy Nilakantan, Arie Zask, and Robert Powers. Journal of the American Chemical Society 2000 122 (40), 9648-9654